Below is the current version of my lectures for the “Genome Science” module — 2nd Year BSc program, academic year 2019-20. Please feel free to use for educational purposes. I will be also happy to get your feedback.
- Lecture 1. Historic intro, genomes and sequencing projects (VT)
- Lecture 2. Sequencing technologies (VT)
- Lecture 3. What is a gene? (VT)
- Lecture 4. Epigenetics overview (PVW) (available on the Moodle)
- Lecture 5. Transcription regulation (VT)
- Lecture 6. Nucleosome positioning and 3D genome organisation (VT)
- Lecture 7. DNA methylation and other DNA modifications (VT)
- Lecture 9. NGS experiments and analysis I: the basics (VT)
- Lecture 10. NGS experiments and analysis II: data integration (VT)
Practicals:
- Practical 1. MNase-seq (wet lab) (available on the Moodle)
- Practical 2. NGS analysis (IT lab). ChIP-seq processing in Galaxy
- Practical 3. NGS analysis (IT lab). Integration of ChIP-seq and RNA-seq data