Thank you for your interest in the Teif lab! We work on gene regulation in stem cell differentiation to cancer using approaches of biophysics, bioinformatics and next generation sequencing (see publications). We also maintain the NucPosDB database and few other resources explained below. Feel free to contact us with suggestions of your resources and events to be included in the databases. 

Our favourite games are cantered around nucleosomes. We are investigating how nucleosomes interact with transcription factors and other chromatin players to fine tune gene regulation in cell differentiation and cancer transitions, and how this fundamental information can be translated in to the clinic to aid patient diagnostics, stratification and monitoring for personalised medicine.

Quantitative Gene RegulationThis web site contains resources relevant to gene regulation, including nucleosome positioning (NucPosDB is a centralised database of experimental nucleosome maps in vivo, cell-free DNA (cfDNA), algorithms to predict nucleosome positioning and computational tools to analyse nucleosome positioning experiments) and protein-DNA binding (e.g. the section TF binding contains information about databases of transcription factors weight matrices, experimental binding datasets and computational tools). A frequently updated section is devoted to upcoming conferences and schools relevant to quantitative gene regulation. Recently we started maintaining the real-time calendar of online events such as webinars. In addition, we maintain a list of undergraduate research opportunities , postdoctoral and PhD fellowships, as well as travel grants. Finally, the Open Science sections contain information about the present and future of science online including the Academic Mastodon/Twitter  and the Fragile Nucleosome online discussion community.