Stable nucleosomes of human genome

Below is the database of regions with stable nucleosome occupancy, calculated for different human cells and on cell-free DNA. This section is part of NucPosDB, a central nucleosome positioning database.

Jump to: NucPosDB front page experimental nucleosome maps in vivo | experimental cfDNA datasets | tools for analysis of nucleosome mapping experiments | tools for prediction of nucleosome maps from DNA sequence | tools for analysis of sequenced cfDNA

The repository below contains 100-bp genomic regions with stable nucleosome occupancies for medical conditions where at least two datasets in several patients are reported by at least two independent laboratories. The stable nucleosomes for remaining datasets can be found in the main cfDNA repository.

cfDNA in breast cancer:

cfDNA breast cancer

  • Stable-nucleosome regions reconstructed based on Snyder et al., 2016  (6 patients, WGS):
    | stable nucleosomes hg19 | stable nucleosomes hg38 | all nucleosomes hg19 | all nucleosomes hg38 |
  • Stable-nucleosome regions reconstructed based on Song et al., 2017 (2 patients, WGS):
    | stable nucleosomes hg19 | stable nucleosomes hg38 | all nucleosomes hg19 | all nucleosomes hg38 |
  • Nucleosome maps based on  Butler et al., 2015  (1 patient, WGS)
    | all nucleosomes hg19 | all nucleosomes hg38 |