Fragile Nucleosome

Fragile Nucleosome (aka #FragileNucleosome) is a discussion group for scientists interested in chromatin and gene regulation. It was established by the initiative of Christine Cucinotta, and is administered by Christine Cucinotta, Hanneke Vlaming, Melvin Noe Gonzalez, Pravrutha Raman, Ben Martin and yours truly. Fragile Nucleosome is active in two spaces: one is the Discord server where several hundred scientists chat informally on scientific matters. You can join the Fragile Nucleosome Discord server. Another activity of the group is the organisation of weekly virtual seminars on Zoom. Our webinars are being conducted on Wednesdays 9am Pacific time (5pm UK, 6pm Central Europe). The schedule of #FragileNucleosome webinars is shown below. Most previous seminars have been recorded and can be viewed at our YouTube channel. Please note that we also maintain the calendar with all webinars related to gene regulation (not limited to #FragileNucleosome) at a separate page

 

Check out our new initiative – the Fragile Nucleosome Journal Club! (It’s separate from the seminar series)

 

Upcoming Seminars


8

July 2020

9am PST, 5pm BST, 

6pm CET, 9.30pm IST

Natalia Kochanova

(Bill Earnshaw Lab, University of Edinburgh)

A multi-layered structure of the interphase chromocenter revealed by proximity-based biotinylation

Tobias Warnecke (Imperial College London)

Histones in archaea

15

July 2020

9am PST, 5pm BST, 

6pm CET, 9.30pm IST

Aleksandra Skrajna
(Robert McGinty Lab, University of North Carolina)
Title TBA
Emma Morrison (Medical College of Wisconsin)
Title TBA

22

July 2020

9am PST, 5pm BST, 

6pm CET, 9.30pm IST

Daria Shlyueva
(Kristian Helin Lab, Memorial Sloan Kettering Cancer Center)
Title TBA
Vijay Ramani (Univesity of California San Fransisco)
Title TBA

Past seminars:

1

April 2020

Hiten Madhani: Epigenetic memory over geological timescales

9:00am (Pacific time)

UCSF, USA

8

April 2020

Toshio Tsukiyama: Regulation of Quiescence through Chromatin


9:00am (Pacific time)

Fred Hutchinson Center, USA

15

April 2020

Susan Gasser: Histone turnover in response to DNA damage: part of the checkpoint response


9:00am (Pacific time)

Friedrich Miescher Institute, Switzerland

29

April 2020

Cynthia Wolberger: Mechanisms of cross-talk between histone ubiquitination and methylation


9:00am (Pacific time)

Johns Hopkins University, USA

6

May 2020

Karolin Luger: An Epi(genetic) Battle: Nucleosomes and the Nuclear Machinery

9:00am (Pacific time)

University of Colorado Boulder, USA

13

May 2020

Tracy Johnson: A histone tale: RNA splicing and coordinated control of gene expression


9:00am (Pacific time)

UCLA, USA

20

May 2020

Sheila Teves: Transcriptional memory and dynamics in embryonic stem cells


9:00am (Pacific time)

University of British Columbia, Canada

27

May 2020

Fred van Leeuwen: Unraveling chromatin mechanisms by DNA barcoding


9:00am (Pacific time)

Netherlands Cancer Institute

3

June 2020

Alistair Boettiger: Visualizing genome folding and gene expression in development

9:00am (Pacific time)

Stanford University, USA

11

June 2020

Don and Ada Olins: Nuclear architectural plasticity and stability in a myeloid cell


9:00am (Pacific time)

University of New England, USA

17

June 2020

Rob Beagrie (Douglas Higgs group): In vivo dynamics of transcription, chromatin and genome organization during mouse erythroid differentiation


9:00am (Pacific time)

University of Oxford, UK

17

June 2020

Siyuan (Steven) Wang: Multiplexed imaging of nucleome architectures in single cells of mammalian tissue


9:30am (Pacific time)

Yale University, USA

24

June 2020

Angelika Feldmann (Rob Klose Lab): Cohesin disrupts polycomb-dependent chromosome interactions in ESCs


9:00am (Pacific time)

University of Oxford, UK

24

June 2020

Andrew Pospisilik (Van Andel Institute) Epigenetics, bistability and probabilistic metabolic disease


9:30am (Pacific time)

Van Andel Institute, USA

1

July 2020

Apoorva Baluapuri (Elmar Wolf Lab): MYC Recruits SPT5 to RNA Pol II to Promote Processive and Directional Transcription Elongation


9:00am (Pacific time)

Biozentrum Würzburg, Germany

1

July 2020

Gabe Zentner: Transcription start sites earn their STRIPEs


9:30am (Pacific time)

Indiana University, USA