Fragile Nucleosome
Fragile Nucleosome (aka #FragileNucleosome) is a discussion group for scientists interested in chromatin and gene regulation. It was established by the initiative of Christine Cucinotta, and is administered by Christine Cucinotta, Hanneke Vlaming, Melvin Noe Gonzalez, Pravrutha Raman, Ben Martin and yours truly. Fragile Nucleosome is active in two spaces: one is the Discord server where several hundred scientists chat informally on scientific matters. You can join the Fragile Nucleosome Discord server. Another activity of the group is the organisation of weekly virtual seminars on Zoom. Our webinars are being conducted on Wednesdays 9am Pacific time (5pm UK, 6pm Central Europe). The schedule of #FragileNucleosome webinars is shown below. Most previous seminars have been recorded and can be viewed at our YouTube channel. Please note that we also maintain the calendar with all webinars related to gene regulation (not limited to #FragileNucleosome) at a separate page.
Check out our new initiative – the Fragile Nucleosome Journal Club! (It’s separate from the seminar series)
Upcoming Seminars
8
July 2020
9am PST, 5pm BST,
6pm CET, 9.30pm IST
Natalia Kochanova
(Bill Earnshaw Lab, University of Edinburgh)
A multi-layered structure of the interphase chromocenter revealed by proximity-based biotinylation
Tobias Warnecke (Imperial College London)
Histones in archaea
15
July 2020
9am PST, 5pm BST,
6pm CET, 9.30pm IST
22
July 2020
9am PST, 5pm BST,
6pm CET, 9.30pm IST
Past seminars:
1
April 2020
Hiten Madhani: Epigenetic memory over geological timescales
9:00am (Pacific time)
UCSF, USA
8
April 2020
Toshio Tsukiyama: Regulation of Quiescence through Chromatin
9:00am (Pacific time)
Fred Hutchinson Center, USA
15
April 2020
Susan Gasser: Histone turnover in response to DNA damage: part of the checkpoint response
9:00am (Pacific time)
Friedrich Miescher Institute, Switzerland
29
April 2020
Cynthia Wolberger: Mechanisms of cross-talk between histone ubiquitination and methylation
9:00am (Pacific time)
Johns Hopkins University, USA
6
May 2020
Karolin Luger: An Epi(genetic) Battle: Nucleosomes and the Nuclear Machinery
9:00am (Pacific time)
University of Colorado Boulder, USA
13
May 2020
Tracy Johnson: A histone tale: RNA splicing and coordinated control of gene expression
9:00am (Pacific time)
UCLA, USA
20
May 2020
Sheila Teves: Transcriptional memory and dynamics in embryonic stem cells
9:00am (Pacific time)
University of British Columbia, Canada
27
May 2020
Fred van Leeuwen: Unraveling chromatin mechanisms by DNA barcoding
9:00am (Pacific time)
Netherlands Cancer Institute
3
June 2020
Alistair Boettiger: Visualizing genome folding and gene expression in development
9:00am (Pacific time)
Stanford University, USA
11
June 2020
Don and Ada Olins: Nuclear architectural plasticity and stability in a myeloid cell
9:00am (Pacific time)
University of New England, USA
17
June 2020
Rob Beagrie (Douglas Higgs group): In vivo dynamics of transcription, chromatin and genome organization during mouse erythroid differentiation
9:00am (Pacific time)
University of Oxford, UK
17
June 2020
Siyuan (Steven) Wang: Multiplexed imaging of nucleome architectures in single cells of mammalian tissue
9:30am (Pacific time)
Yale University, USA
24
June 2020
Angelika Feldmann (Rob Klose Lab): Cohesin disrupts polycomb-dependent chromosome interactions in ESCs
9:00am (Pacific time)
University of Oxford, UK
24
June 2020
Andrew Pospisilik (Van Andel Institute) Epigenetics, bistability and probabilistic metabolic disease
9:30am (Pacific time)
Van Andel Institute, USA
1
July 2020
Apoorva Baluapuri (Elmar Wolf Lab): MYC Recruits SPT5 to RNA Pol II to Promote Processive and Directional Transcription Elongation
9:00am (Pacific time)
Biozentrum Würzburg, Germany
1
July 2020
Gabe Zentner: Transcription start sites earn their STRIPEs
9:30am (Pacific time)
Indiana University, USA