NucPosDB is a manually curated database based on more than 400 publications reporting nucleosome maps in vivo across different cell types and conditions, cell-free DNA datasets in human patients and model organisms as well as software for computational analysis  and  modelling of nucleosome positioning as well as “nucleosomics” for medical diagnostics.


Sequenced cell-free DNA (cfDNA) datasets

This is the most recent addition to the database, which is expanding quickly. It contains sequenced cell-free DNA (cfDNA) from body liquids such as blood plasma, urine, cerebrospinal liquid, etc. 


Experimental nucleosome maps in vivo  

This section of the database is devoted to experimental datasets such as MNase-seq, MNase-assisted H3 ChIP-seq, chemical mapping, etc, conducted in cells or tissues. Currently contains data from more than 200 publications.

 

 

COMPUTATIONAL ANALYSIS

 

Prediction of nucleosome positioning

This list currently contains 22 software tools for prediction of nucleosome positioning from DNA sequence based on biophysics or bioinformatics approaches

 

 

 

Analysis of experimental nucleosomics data

This list currently contains  30 software solutions for analysis of MNase-seq, chemical nucleosome mapping and other experimental techniques to map nucleosomes

 

Related repositories:

DNA-protein binding: data, tools & models