NucPosDB is a manually curated database based on more than 300 publications reporting more than 1,000 experimental nucleosome maps across different cell types and conditions, cell-free DNA datasets in human patients and model organisms as well as computational tools for the analysis of nucleosome positioning experiments and modelling.


Sequenced cell-free DNA (cfDNA) datasets

This is the most recent addition to the database, which is expanding quickly. It contains sequenced cell-free DNA (cfDNA) from body liquids such as blood plasma, urine, cerebrospinal liquid, etc. 


Experimental nucleosome maps in vivo  

This section of the database is devoted to experimental datasets such as MNase-seq, MNase-assisted H3 ChIP-seq, chemical mapping, etc, conducted in cells or tissues. Currently contains data from more than 200 publications.

 

 

SOFTWARE REPOSITORY

 

Prediction of nucleosome positioning

This list currently contains 22 software tools for prediction of nucleosome positioning from DNA sequence based on biophysics or bioinformatics approaches

 

 

 

Analysis of nucleosome positioning experiments

This list currently contains  30 software solutions for analysis of MNase-seq, chemical nucleosome mapping and other experimental techniques to map nucleosomes

 

Related databases:

DNA-protein binding: data, tools & models