Calendar of gene regulation events online
The calendar below lists webinars and meetings relevant to gene regulation. All times below are in GMT (London, UK). The link to export these events to Outlook or Google Calendar is at the bottom of this page. The calendar below includes all virtual events related to gene regulation, not limited to those organised by Fragile Nucleosome. To add your own virtual event that is not yet in our list, please email [email protected]. For a list of conferences and schools in the area of gene regulation, see the separate page “conferences, meetings and schools”. Also, have a look at complementary lists of webinars at The Node (developmental biology and related subjects), Physics of Life (biophysics) and mathseminars.org (mathematics & physics).
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Functional organization of the genome in 3D
September 11, 2020 @ 3:00 pm - 5:00 pm UTC+0
Free
The Biology Department of LUMS is pleased to invite Dr. Stefan Schoenfelder for a talk about “Functional organization of the genome in 3D” on Sept 11 at 3 p.m. Pakistan & 11 a.m. UK time. Live streaming at https://www.facebook.com/sbasselums/
Abstract: The three-dimensional organisation of the genome is tightly linked to its function. The cell-type specific folding of the DNA enables gene regulatory elements, including promoters and enhancers, to interact, in some cases bridging distances of hundreds of kilobases. These enhancer-promoter contacts are thought to be crucial for gene expression control. I will discuss recent progress in the methodology to map the 3D organisation of chromatin in mammalian nuclei genome-wide, illustrate on examples how enhancer-promoter contacts dynamically respond to signalling cues and are rewired during cell fate transitions, and highlight some of the major challenges and open questions in the field.
Biography: Dr. Stefan Schoenfelder studied molecular biology at the University of Heidelberg, Germany. He received his PhD in 2005 from Centre for Molecular Biology in Heidelberg, studying the mechanism of a transcriptional silencer in the mouse H19/Igf2 imprinting control region. In 2005, he joined the lab of Peter Fraser at the Babraham Institute in Cambridge (UK), where he first focused on the spatial organisation of transcription in mouse erythroid cells. He established a novel method to map long-range enhancer-promoter interactions genome-wide at high resolution. Since 2018, Dr. Schoenfelder is a group leader at the Babraham Institute. His current research focus is to decipher how cis-regulatory variation underpins the functional heterogeneity between human induced pluripotent stem cells.